Details. signs of inflammation in the lining of your stomach - pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, fever. I'm contemplating getting infusions again but I've always been a bit worried that they could cause issues in the long run. (Hemoglobin is a protein thats found in your red blood cells.). However, consuming large amounts of alcohol can actually cause anemia in some people. <> Allergic reactions typically occur the first time your body is exposed to a drug. Here are answers to some frequently asked questions about Injectafer. In Canada - Call your doctor for medical advice about side effects. You should not receive Venofer if you have known allergies to iron sucrose. Before taking Injectafer, talk with your doctor about your health history. Not all possible drug interactions are listed here. In the second group, some people switched from taking iron by mouth to taking Injectafer. After 5 weeks of treatment: This study didnt determine if either drug was better than the other. Call your doctor for medical advice about side effects. Answer by DrLact: About Venofer usage in lactation. Consult your pharmacist or local waste disposal company. However, not treating iron deficiency anemia during pregnancy may cause complications such as premature birth or low birth weight. Side effects: DayQuil can cause side effects such as drowsiness, dizziness, nausea, vomiting, and stomach upset. Fortunately, knowing how longside effectslast can help those suffering know what to donext. Allergic reactions are most likely to occur within 30 minutes of receiving Venofer. Some people may also experience skin irritation from the adhesive tape and other medical equipment used during the procedure. Venofer may reduce the absorption of iron preparations taken by mouth. And the drug has also been studied in children with IDA who have inflammatory bowel disease (IBD). Other side effects include: Common (may affect up to 1 in 10 users) Temporary taste changes (especially metallic taste) Low blood pressure or high blood pressure. Notify your healthcare provider of all medical conditions and any medications, including supplements you are taking. Brand-name medications usually cost more than generics. Learn more about these, as well as the symptoms, diagnosis, and treatments. HRT, like other medications, does have some side effects and these are thought to be quite common. Only 10 mg may be excreted by the body the next time it goes through the liver, and possibly only 5 mg the nextpass. Reactions around the injection/infusion site, such as pain, irritation, itching, bleeding, or discoloration after leakage of injection into the skin. And this can lead to anemia, including IDA. The potential side effects of Daxxify are nearly identical to that of Botox bruising, headaches, and droopy eyelids with one big difference: They could last longer. Side effectswill last a very long time if the cause of them is not resolved. The dosing for iron replacement treatment in pediatric patients less than 2 years old with Peritoneal or Hemodialysis-Dependent CKD or Non-Dialysis-Dependent CKD have not been established. Venofer is used to treat iron deficiency anemia in people with kidney disease. Clinical trials showed that Injectafer is effective in increasing hemoglobin levels in people with iron deficiency anemia (IDA). Cholesterolmedication may reduce the risk of a stroke but it can decrease the quality of life for some people but causingweight gain, dizziness, nausea, and musclepain. The way thatprescription drugsand evenover-the-countermedications interact with a body is influenced by manyfactors. I had Venofer infusions, 2 rounds now in the span of three years. If you do breastfeed while youre taking Injectafer, the drugs manufacturer recommends that you monitor your child for side effects of the drug. Tell your doctor right away if you have any serious side effects, including: abdominal pain, chest pain, irregular heartbeat (arrhythmias), pressure in the chest, severe headache and blurred vision (hypertension), problems with your dialysis access site (graft). As with most drugs, some people can have an allergic reaction after taking Injectafer. In this study, compared with their level before treatment: Injectafer isnt currently approved for use in children. Upset stomach or throwing up. If your symptoms or health problems do not get better or if they become worse, call your doctor. fever. Consult your doctor before breast-feeding. In clinical studies, diarrhea was reported in less than 1% of people taking Injectafer. Potential injection site discoloration has happened. With slow IV injection, the drug is given as a single, slow injection into your vein. TheNational Instituteof Health (NIH) and the U.S. Food andDrug Administration(FDA) monitor theside effectsof new and approved medications to ensure safety. For instance, those who are taking other medications or supplements as part of home remedies may continue to suffer from the ill effects of their new medication because they dontinteract. Injectafer isnt available in a generic form. Many people using this medication do not have serious side effects.Severe dizziness or fainting (hypotension) may occur while you are receiving IV iron. There are currently no generic forms of either drug. It belongs to a class of medications called iron replacement products. pain in the arms or legs. Iron infusions are given directly into a vein. You may report side effects to the FDA at 1-800-332-1088. All rights reserved. Venofer (iron sucrose) can also be mixed in a saline solution and given through an IV over a longer time. If this happens to you, your doctor may recommend that you receive another treatment course of Injectafer. 12 Medicines That Could Help, List Venofer Vial side effects by likelihood and severity. Effectiveness of Injectafer compared with iron thats taken by mouth. Injectafer contains the active drug ferric carboxymaltose. In the US - Call your doctor for medical advice about side effects. In clinical trials, pregnant females* who took Injectafer didnt have any negative outcomes, such as premature delivery or pregnancy loss. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. Keep all drugs in a safe place. These lists contain up to 10 of the most common mild side effects that can occur with Injectafer, with Feraheme, or with both drugs (when taken individually). You may wonder how Injectafer compares with other medications that are prescribed for similar uses. How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction. All patients receiving Venofer require periodic blood tests to monitor the amount of iron in the blood. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. Remember that it is best to get your vitamins and minerals from food whenever possible. Why is the range so wide? Now I've just got mild nausea and have felt faint/dizzy a few times which is rare for me. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Injectafer contains the active drug ferric carboxymaltose. WARNINGS/CAUTIONS: Serious hypersensitivity reactions, including anaphylactic-type reactions (itching, hives, swelling, wheezing, difficulty breathing, fainting and/or other allergy symptoms), some of which have been life threatening and fatal, have happened in patients receiving Venofer. generalized weakness. (A class of medications describes a group of drugs that work in the same way.). For more information about Injectafers approved uses, see the section Injectafer uses below. Review our medical disclaimer. SIDE EFFECTS: Muscle cramps, nausea, vomiting, strange taste in the mouth, diarrhea, constipation, headache, cough, back pain, joint pain, dizziness, or swelling of the arms/legs may occur. However, since peoples bodies react so differently to drugs, they often have to change their stance on certain drugs. Learn how to store and discard medical supplies safely. Grapefruitjuice may be healthy for people to drink, but it can cause someseriousside effects. taste impairment. In order for your body to make RBCs, your bone marrow needs a hormone called erythropoietin (EPO). Low blood pressure. Your body may also need more iron if you use the drug erythropoietin to help make new red blood cells.Iron is an important part of your red blood cells and is needed to transport oxygen in the body. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. Laboratory tests (such as complete blood count, ferritin, transferrin, total iron binding capacity-TIBC) should be performed periodically to monitor your progress or check for side effects. If needed, theyll recommend treatment, including certain medications. This medication is given by injection into a vein as directed by your doctor. Injectafer infusions are given over a period of at least 15 minutes. Pain in your limbs. This medicine is used to treat "iron-poor" blood (anemia) in people with long-term kidney disease. Learn how to store and discard medical supplies safely. Brandon ColbyMD, a medical expert specializing in preventive medicine and clinicalgenomics. Injectafer is available only as a brand-name medication. dizziness. 2 Protocol for Intravenous iron sucrose - Venofer 2.1 Dosage The total cumulative dose of Venofer should be calculated using the table below. Always review your medical history with the treatingphysician. 1xo`[kg'#KS#.#`uv:PM1+Ob`>y/8:6Ghl:y9B+-,9m[ These drugs have been compared in a clinical trial of adults with both IDA and CKD who didnt need dialysis. If you think there has been an overdose, call your poison control center or get medical care right away. No, Injectafer itself wont make you gain weight. Venofer Side Effects. If you miss an appointment for your Injectafer dose, youll need to call your doctors office. This medicine is sometimes given slowly, and the infusion can take up to 2.5 hours to complete. This survey is being conducted by the WebMD marketing sciences department. Venofer may cause significant hypotension (decreased blood pressure). This medication is given by injection into a vein as directed by your doctor. 2. monitor along with your hemoglobin and red blood cell count: The Venofer patient brochure provides information and support for CKD patients (2 years and older) with IDA. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Since side effects are similar between 150 mg and 300 mg, a larger dose may increase severity or frequency of side effects. How is Venofer (iron sucrose) given? How long it takes for the bodyto break down the meds matters and some peoples bodies simply take longer than others. Its given by either intravenous (IV) infusion or slow IV injection. Learn about uses, cost, how it works, and more. Do not double the dose to catch up. Its not known if Injectafer is safe to take during pregnancy. Your body then uses the iron from Injectafer to make hemoglobin and new RBCs. This is not a complete list of side effects and others may occur. Drug interactions may change how your medications work or increase your risk for serious side effects. * This is a partial list of mild side effects from Injectafer. Heart failure: Could a low sodium diet sometimes do more harm than good? This document does not contain all possible drug interactions. And this type of reaction is possible even if you didnt have a reaction to your first dose of the drug. Injectafer can cause low blood levels of phosphorus, which is a condition called hypophosphatemia. Venofer is not for treating other forms of anemia not caused by iron deficiency. However, some people may have weight changes as they have improvement in their anemia, which Injectafer is used to treat. A very serious allergic reaction to this drug is unlikely, but get medical help right away if it occurs. This is not a complete list of possible side effects. As a result, you may not make as much EPO as usual. This gives a total cumulative dose of 1,500 mg of Injectafer. An iron infusion is a way to increase the body's iron levels quickly. There are 2 tests that your doctor will likely
With slow IV injection, the drug is given as a single, slow injection into your vein. In clinical studies, people who took Injectafer still had iron in their system that was released by the drug 24 days after theyd gotten their injection. Spacing your Injectafer doses out at least 7 days helps to reduce your risk of side effects. Terminal half-life ranges from 7 to 12 hours. intense abdominal pain. Boxed warnings alert doctors and patients about drug effects that may be dangerous. Call your doctor right away if youre having a severe allergic reaction to Injectafer, even if youve had doses of the drug in the past without any problems. If you have diarrhea while youre taking Injectafer, call your doctor. Venofer treatment may be repeated if iron deficiency reoccurs. This is why the FDA hasa programcalledMedWatchthat encourages Americans to report adversereactions. People with IDA have low blood levels of hemoglobin. As with all medications, the cost of Injectafer can vary. Be ready to tell or show what was taken, how much, and when it happened. If you notice any changes to your normal blood pressure, call your doctor right away. One class of immune checkpoint inhibitors targets the protein PD-1, which acts as a brake to keep the immune system in check. Call your doctor for medical advice about side effects. Your doctor will recommend whether you should stop taking your multivitamin or any other supplements. This information should not be used to decide whether or not to take Venofer or any other medicine. They can recommend if this is safe for you to do. For reasons we dont fully understand, some peoples immune system gets over-activated when the drug enters their body. As described just above in the Allergic reaction section, some people may have an allergic reaction after getting a dose of Injectafer. Iron infusion benefits. It will take about three weeks to feel the effects but your fatigue will disappear and you will feel like a new person. Your doctor will go over your
Iron is important for many functions in the body, especially for the transport of oxygen in the blood. Iron sucrose can also be mixed in a saline solution and given through an IV over a longer time. Some people only need one treatment course of Injectafer. Patients with iron-deficiency anemia who are having high blood loss surgery (> 500 ml) within the next 2 months and need to replace iron quickly. And this would give you a total cumulative Injectafer dose of 1,440 mg. Injectafer should be given in two doses. Common MRI side effects include dizziness, anxiety, headache, nausea, hearing loud noises, and feeling chilled or hot in the MRI scanner. . Venofer is given as an infusion into a vein. Your healthcare provider will watch you closely for 30 minutes after each dose. If administering via IV infusion, up to 750 mg of Injectafer should be diluted in no more than 250 mL of sterile 0.9% sodium chloride solution (NaCl). During Injectafer treatment, your doctor will likely order blood tests. You should always consult your doctor or another healthcare professional before taking any medication. Data on file, American Regent, Inc. 1. Injectafer contains the active drug ferric carboxymaltose, while Feraheme contains the active drug ferumoxytol. Find out what health conditions may be a health risk when taken with Venofer Vial Change in taste. People who weigh less than 110 lb (about 50 kg) will receive two separate Injectafer doses of 15 mg/kg of body weight. In one study, people were given either Injectafer or an iron replacement drug called Venofer. Most of these side effects may go away within a few days or a couple of weeks. The drug helps increase your hemoglobin level back to a value thats within the normal range. 2022 American Regent, Inc.PP-VE-US-0016 (v6.0)1/2022, Iron is also necessary for your bone marrow to build healthy new red blood cells and provide oxygen to your organs and tissues through hemoglobin, If you or your child has been prescribed Venofer, its based on your blood work, which shows how many red blood cells you have and whether you have enough iron in your blood cells, If you are iron deficient, raising your iron levels can help increase your hemoglobin levels, Treating your anemia may help prevent future health problems, Over time, untreated IDA can cause heart problems; if you already have heart problems, it can make those problems worse, Venofer is given intravenously (through an IV) and
Storage Condition Store in a cool and dry place protected from light. Mental healthdisorders like depression may requireantidepressantsto treat. Tell your doctor if you are taking iron supplements or other iron-based oral medications. What is Venofer? For more information and to find out if youre eligible for support, call 877-4-IV-IRON (877-448-4766) or visit the program website. Dilute Venofer in a maximum of 250 mL of 0.9% NaCl. Heres some detail on certain side effects this drug may cause. A healthcare provider will give you this injection. Throw away unused or expired drugs. * Feraheme has a boxed warning for this side effect. So the goal of anemia treatment is to increase your hemoglobin level back to a value thats within a normal range. Examples of other drugs that may be used to treat IDA include: Your doctor will recommend the drug thats right for you depending on the severity of your anemia and any other medical conditions you may have. To make sure Venofer injection is safe for you, tell your doctor if you have: hemochromatosis or iron overload (the buildup of excess iron). For this purpose, Injectafer is approved for use in adults who either: Venofer is also approved to treat IDA. On the other hand, some people may have a poor appetite that goes away when their anemia is treated. This way, if you have an allergic reaction to Injectafer, your healthcare professional can treat your reaction. (And Injectafer is used to treat IDA.) To help make sure that you dont miss an appointment for your Injectafer dose, try setting an appointment reminder on your phone. Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when Venofer is injected. Venofer 100 mg iron/5 mL intravenous solution, Venofer 50 mg iron/2.5 mL intravenous solution, Venofer 200 mg iron/10 mL intravenous solution, Select a condition to view a list of medication options. Symptoms include shock, dangerously low blood pressure, loss of consciousness, and/or collapse. There may be risks to the mother and fetus associated with untreated IDA in pregnancy. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics(ACMG), an Associate of the American College of Preventive Medicine(ACPM), and a member of the National Society of Genetic Counselors(NSGC). Some drugs may have another patient information leaflet. A delayed reaction can occur in two different ways: It can happen hours or days after you receive a drug, or it can happen after a second (or later) dose of a drug. Blood tests may be needed to check for unwanted effects. MNT is the registered trade mark of Healthline Media. Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. <> Venofer (iron sucrose) is given by injection into a vein as directed by your doctor. But for most people whove developed hypophosphatemia with Injectafer, the condition resolved within 3 months. Also, keep in mind that if your anemia is causing certain symptoms, treatment with Injectafer may help those symptoms go away. To learn about other mild side effects, talk with your doctor or pharmacist, or see Injectafers package insert. However, there has been a report of delayed allergic reaction in someone receiving a second dose of Injectafer. But keep in mind that in this study, delayed allergic reaction only occurred in one person. Venofer (iron sucrose injection, USP) Rx Only DESCRIPTION Venofer (iron sucrose injection, USP) is a brown, sterile, aqueous, complex of polynuclear iron (III)-hydroxide in sucrose for intravenous use. If you have questions about the blood tests youll need to have done to monitor your anemia, talk with your doctor. Its not known if Injectafer is safe to use during pregnancy. Pain, swelling, or redness at the injection site may occur. Theyll likely have you stop taking the pills while youre using Injectafer. People with IDA have low blood levels of hemoglobin. Serious side effects from Injectafer arent common, but they can occur. Use Venofer as ordered by your doctor. The infusion will take between 15-30 minutes if it is given in. Maintain a well-balanced diet, and follow any dietary guidelines as directed by your doctor. Total cumulative Venofer dose = number of 100mg ampoules for Hb increase. You may wonder how Injectafer compares with other medications that are prescribed for similar uses. After receiving IV iron therapy, you will be monitored for 30 minutes to make sure you do not have an allergic reaction or a drop in blood pressure. Venofer (iron sucrose injection, USP) is indicated for the treatment of iron deficiency anemia (IDA) in adult and pediatric (2 years of age and older) patients with chronic kidney disease (CKD), and is administered only by or under the supervision of your healthcare provider.
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